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AZ10417808

詳情介紹：

Product details
Product details
Purpose	A non-peptidic caspase-3 inhibitor
Characteristics	AZ10417808 is a selective non-peptide inhibitor of caspase-3 (Ki = 247 nM); displays > 40-fold selectivity over caspases 1, 2, 6, 7 and 8 (Ki > 10 μM). Completely blocks staurosporine-induced intracellular DEVDase activity in SH-SY5Y cells (IC?? = 14.9 μM).
Purity	≥ 98?% by HPLC
Chemical Name	2-(3,4-dichloroanilino)-6-nitro-4-oxo-N-prop-2-enyl-1H-quinazoline-8-carboxamide
Formula	C??H??Cl?N?O?
Permeability	Cell-permeable
Solubility	DMSO (~ 10 mg/ml)

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