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產(chǎn)品名稱:HEK-293CellsIgGisotypecontrol(Histag)
產(chǎn)品型號:
產(chǎn)品廠商:ACROBiosystems
產(chǎn)品文檔:
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簡單介紹:
HEK-293CellsIgGisotypecontrol(Histag)
詳情介紹:
Product details
Product details
Isotype
IgG
Fragment
Fc fragment
Characteristics
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27 kDa. The protein migrates as 34 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity
>95?% as determined by SDS-PAGE.
Endotoxin Level
Less than 1.0 EU per μg by the LAL method.
Target details
Target details
Background
Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
Molecular Weight
27 kDa
UniProt
P01857
Research Area
Secondary Antibodies
Application Details
Application Details
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
Handling
Format
Lyophilized
Reconstitution
Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer
50 mM Tris, 100 mM Glycine,?pH 7.5
Storage
-20 °C
Images
Images
Supplier Images
Human IgG1 Fc, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained ...
×
Human IgG1 Fc, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Human IgG1 Fc, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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