99国产精品视频免费观看_国产一区毛片_久久激情视频免费观看_国产成人aa在线观看网站站

產品詳情
所在位置: 首頁> 產品目錄> 抑制劑>
  • 產品名稱:Caspase-9InhibitorZ-LEHD-FMK

  • 產品型號:
  • 產品廠商:Biovision
  • 產品文檔:
你添加了1件商品 查看購物車
簡單介紹:
Caspase-9InhibitorZ-LEHD-FMK
詳情介紹:
Purpose A caspase-9 inhibitor
Sequence Z-Leu-Glu(OMe)-His-Asp(OMe)-FMK
Characteristics PubChem CID: 44135217
A synthetic peptide that irreversibly inhibits caspase-9 and related caspase activity. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Purity > 98?% by HPLC
Chemical Name Z-LEHD-FMK, Caspase-9 Inhibitor, LEHD-fluoromethylketone
Formula C??H??FN?O??
Permeability Cell-permeable
Solubility DMSO
Molecular Weight 690.7 g/mol
Application Notes Centrifuge the vial prior to opening. We recommend using 1000-5000X dilutions for inhibiting caspase-9 activity in cell culture (e.g., Add 1 μL to 1-5 mL of culture medium). The optimal doses may vary for different cells and culture conditions.
Restrictions For Research Use only
Format Liquid
Concentration 10 mM
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 12 months
Supplier Images
 image for Caspase-9 Inhibitor Z-LEHD-FMK (ABIN412392) Caspase-9 Inhibitor Z-LEHD-FMK
Product cited in: Ying, Yang, Tsai, Hsieh, Huang, Bau, Hsieh: "Fisetin induces apoptosis in human cervical cancer HeLa cells through ERK1/2-mediated activation of caspase-8-/caspase-3-dependent pathway." in: Archives of toxicology, 2011 (PubMed).

Jin, Ojcius, Sun, Dong, Luo, Mao, Yan: "Leptospira interrogans induces apoptosis in macrophages via caspase-8- and caspase-3-dependent pathways." in: Infection and immunity, Vol. 77, Issue 2, pp. 799-809, 2009 (PubMed).

Deng, Yin, Lu, Cai, Yin: "The apoptotic effect of brucine from the seed of Strychnos nux-vomica on human hepatoma cells is mediated via Bcl-2 and Ca2+ involved mitochondrial pathway." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 91, Issue 1, pp. 59-69, 2006 (PubMed).

Teachey, Obzut, Axsom, Choi, Goldsmith, Hall, Hulitt, Manno, Maris, Rhodin, Sullivan, Brown, Grupp: "Rapamycin improves lymphoproliferative disease in murine autoimmune lymphoproliferative syndrome (ALPS)." in: Blood, Vol. 108, Issue 6, pp. 1965-71, 2006 (PubMed).

Gillet, Dewals, Farnir, de Leval, Vanderplasschen: "Bovine herpesvirus 4 induces apoptosis of human carcinoma cell lines in vitro and in vivo." in: Cancer research, Vol. 65, Issue 20, pp. 9463-72, 2005 (PubMed).

Yao, Nguyen, Pike: "Beta-amyloid-induced neuronal apoptosis involves c-Jun N-terminal kinase-dependent downregulation of Bcl-w." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 25, Issue 5, pp. 1149-58, 2005 (PubMed).

Beaupre, Cepero, Obeng, Boise, Lichtenheld: "R115777 induces Ras-independent apoptosis of myeloma cells via multiple intrinsic pathways." in: Molecular cancer therapeutics, Vol. 3, Issue 2, pp. 179-86, 2004 (PubMed).

Song, Zhou, Kim, Shapiro, Liu, Ferran, Choi, Otterbein: "Carbon monoxide promotes Fas/CD95-induced apoptosis in Jurkat cells." in: The Journal of biological chemistry, Vol. 279, Issue 43, pp. 44327-34, 2004 (PubMed).

Wang, Grégori, Hullinger, Andrisani et al.: "Sustained activation of p38 mitogen-activated protein kinase and c-Jun N-terminal kinase pathways by hepatitis B virus X protein mediates apoptosis via induction of Fas/FasL and tumor necrosis factor ..." in: Molecular and cellular biology, Vol. 24, Issue 23, pp. 10352-65, 2004 (PubMed).

Morishima, Nakanishi, Takenouchi, Shibata, Yasuhiko: "An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12." in: The Journal of biological chemistry, Vol. 277, Issue 37, pp. 34287-94, 2002 (PubMed).

Yen, Mar, Craciunescu, Edwards, Zeisel: "Deficiency in methionine, tryptophan, isoleucine, or choline induces apoptosis in cultured cells." in: The Journal of nutrition, Vol. 132, Issue 7, pp. 1840-7, 2002 (PubMed).

Chatterjee, Brite, Matsumura: "Induction of apoptosis of integrin-expressing human prostate cancer cells by cyclic Arg-Gly-Asp peptides." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 7, Issue 10, pp. 3006-11, 2001 (PubMed).

主站蜘蛛池模板: 盘山县| 革吉县| 达孜县| 嘉荫县| 滦南县| 宝应县| 丽江市| 塘沽区| 香港 | 香河县| 乌兰察布市| 花垣县| 德江县| 长沙市| 临湘市| 靖宇县| 康保县| 济宁市| 化德县| 昭觉县| 曲周县| 珠海市| 盐池县| 揭阳市| 阜平县| 图木舒克市| 怀来县| 嘉祥县| 全南县| 长兴县| 工布江达县| 清原| 儋州市| 保德县| 天长市| 青岛市| 武邑县| 特克斯县| 长宁县| 上思县| 襄汾县|