產品詳情
簡單介紹:
PurinergicReceptorP2X,Ligand-GatedIonChannel,7(P2RX7)(MiddleRegion)Peptide
詳情介紹:
Blocked Antibody | anti-P2RX7 antibody (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7) (Middle Region) (ABIN2776334) |
Characteristics | This is a synthetic peptide designed for use in combination with anti-P2RX7 antibody (Catalog #: ARP35517_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. |
Purification | Purified |
Background |
The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Alias Symbols: MGC20089, P2X7 Protein Interaction Partner: ACTB,EMP3,PANX1,SVIL Protein Size: 149 |
Molecular Weight | 16 kDa |
Gene ID | 5027 |
NCBI Accession | NM_177427, NP_803176 |
UniProt | Q99572 |
Research Area | Neurology |
Application Notes | Each Investigator should determine their own optimal working dilution for specific applications. |
Restrictions | For Research Use only |
Format | Lyophilized |
Reconstitution | Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS. |
Concentration | 1 mg/mL |
Buffer | Final peptide concentration is 1 mg/mL in PBS. |
Handling Advice | Avoid repeated freeze-thaw cycles. |
Storage | -20 °C |
Storage Comment | For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |