99国产精品视频免费观看_国产一区毛片_久久激情视频免费观看_国产成人aa在线观看网站站

產品詳情

  • 產品名稱：HEK-293CellsIgG2IsotypeControl

  • 產品型號：
  • 產品廠商：ACROBiosystems
  • 產品文檔：
你添加了1件商品 查看購物車
簡單介紹：
HEK-293CellsIgG2IsotypeControl
詳情介紹：
Isotype IgG2
Characteristics This protein carries no "tag". The protein has a calculated MW of 25.7 kDa. The protein migrates as 33-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity >95?% as determined by SDS-PAGE.
Sterility 0.22 μm filtered
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
ProductDetails: Biological Activity Comment Biological Activity: Measured by its ability to bind rhCD32a (Catalog # CDA-H5221) in a functional ELISA.
Background Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement. The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis. Ig gamma-2 chain Fc region contains two constant regions of IgG2 H chain (CH2, CH3).
Molecular Weight 25.7 kDa
UniProt P01859
Research Area Secondary Antibodies
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer 50 mM Tris, 100 mM Glycine,?pH 7.5
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
Supplier Images
SDS-PAGE (SDS) image for HEK-293 Cells IgG2 Isotype Control (ABIN2181275) Human IgG2 Fc, Tag Free on SDS-PAGE under reducing (R) and no-reducing (NR) condition...
Background publications Sikorav, Auffray, Rougeon: "Structure of the constant and 3' untranslated regions of the murine Balb/c gamma 2a heavy chain messenger RNA." in: Nucleic acids research, Vol. 8, Issue 14, pp. 3143-55, 1981 (PubMed).

Ollo, Auffray, Morchamps, Rougeon: "Comparison of mouse immunoglobulin gamma 2a and gamma 2b chain genes suggests that exons can be exchanged between genes in a multigenic family." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 78, Issue 4, pp. 2442-6, 1981 (PubMed).

主站蜘蛛池模板： 渭南市| 比如县| 图木舒克市| 彭阳县| 遵义县| 和平区| 北安市| 富民县| 密云县| 新津县| 兴隆县| 岳池县| 通道| 江达县| 且末县| 龙口市| 拉孜县| 德令哈市| 桦甸市| 五莲县| 岳西县| 太仓市| 清水河县| 文水县| 孝义市| 玛曲县| 江安县| 昆山市| 和田市| 新邵县| 临漳县| 卢龙县| 潼关县| 来安县| 泸水县| 徐水县| 义乌市| 雷山县| 武乡县| 佳木斯市| 桦川县|