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  • 產品名稱：BML-210

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簡單介紹：
BML-210
詳情介紹：
Characteristics Potent HDAC Inhibitor
Increases A549 acetylated histone levels
Inhibits transcription factor FOXO3 by SIRT
Background Inhibition of histone deacetylase (HDAC) enzymes by compounds such as trichostatin A can have wide ranging effects in cancer, cell differentiation, and other aspects of gene expression regulation. BML-210 is a small molecule inhibitor of HDAC with an IC50 value of 5-10 uM when tested in HeLa cell nuclear extracts. BML-210 also inhibits the deacetylation of the transcription factor FOXO3 by mammalian SIRT1 in cells oxidatively stressed by hydrogen peroxide.
CAS-No 537034-17-6
Restrictions For Research Use only
Storage 4 °C
Supplier Images
image for BML-210 (ABIN1439980) BML-210
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