產品詳情
簡單介紹:
ARRY380
詳情介紹:
Purpose | HER2 is a member of the human epidermal growth factor receptor (HER/EGFR/ERBB) family. Amplification or overexpression of this oncogene has been shown to play an important role in the development and progression of certain aggressive types of breast cancer. ARRY-380 is an orally bioavailable inhibitor of the human epidermal growth factor receptor tyrosine kinase ErbB-2 (also called HER2) with potential antineoplastic activity. |
Characteristics |
Target: EGFR inhibitor, HER2 inhibitor Receptor: EGFR/HER2/p95-HER2 |
Purification | All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality. |
Purity | 99?% + |
Formula | C29H27N7O4S |
Solubility | DMSO > 10mM |
Molecular Weight | 569.63 g/mol |
CAS-No | 937265-83-3 |
Application Notes | Optimal working dilution should be determined by the investigator. |
Restrictions | For Research Use only |
Format | Solid |
Storage | -20 °C |
Storage Comment |
For the majority of compounds, they could be dissolved in DMSO or other organic solvent. Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience. Several freeze/thaw cycles should not damage the activity of our small molecule products. However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours. |
Expiry Date | 24 months |