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產品名稱:Rabbitanti-HumanImmunoglobulinJPolypeptide,LinkerProteinForImmunoglobulinalphaa
產品型號:
產品廠商:OriGene
產品文檔:
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簡單介紹:
Rabbitanti-HumanImmunoglobulinJPolypeptide,LinkerProteinForImmunoglobulinalphaandmuPolypeptides(IGJ)(C-Term),(JoiningChain)Antibody
詳情介紹:
Product details
Product details
Immunogen
A synthetic peptide derived from near C-terminus of Human J-chain protein.
Specificity
This antibody detects Immunoglobulin J chain. Cellular localisation: Cytoplasm.
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Immunoaffinity Chromatography
Target details
Target details
Alternative Name
Immunoglobulin J Chain
Background
J chain is a small glycopeptide with MW of 15?kDa. It is structurally unrelated to heavy or light chains, but is synthesized by all plasma cells that secrete polymeric immunoglobulins. J chain is linked to IgA and IgM by disulfide bonds, however, it has been detected in IgG- and IgD-containing cells. J chains are present in a large proportion of the immunoglobulin-positive cells in the germinal centers of the tonsils and lymph nodes. B cells discrete J chain at an early stage of differentiation with the expression persisting in those cells destined to produce IgA or IgM.Synonyms: IGCJ, IGJ
Molecular Weight
15 kDa
Gene ID
3512
NCBI Accession
NP_653247
UniProt
P01591
Application Details
Application Details
Application Notes
Optimal working dilutions should be determined experimentally by the investigator.
Restrictions
For Research Use only
Handling
Handling
Format
Liquid
Buffer
PBS,?pH 7.6 with 1?% BSA and less than 0.1?% Sodium Azide
Preservative
Sodium azide
Precaution of Use
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Storage
4 °C
Storage Comment
Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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