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  • 產品名稱：rPhrixotoxin-1

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簡單介紹：
rPhrixotoxin-1
詳情介紹：
Sequence YCQKWMWTCD SARKCCEGLV CRLWCKKII.
Specificity Phrixotoxin-1 blocks specifically and reversibly Kv4.2 and Kv4.3 channels1.
Characteristics Source: Phrixotrichus auratus (Chilean copper tarantula).
Molecular formula: C156H239N44O37S7.
Disulfide bonds between Cys2-Cys16, Cys9-Cys21, and Cys15-Cys25.
Purity > 98 %
Molecular Weight 3549
Application Notes 10-100 nM
Comment

k-theraphotoxin-Ps1a, k-TRTX-Ps1a, PaTX1
Restrictions For Research Use only
Format Lyophilized
Reconstitution Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).
Concentration after reconstitution: Dissolving 50g in 1.409 ml will provide a stock solution of 10 M.
Handling Advice Soluble in Water.
Product cited in: Chagot, Escoubas, Villegas, Bernard, Ferrat, Corzo, Lazdunski, Darbon: "Solution structure of Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels from the venom of the theraphosid spider Phrixotrichus auratus." in: Protein science : a publication of the Protein Society, Vol. 13, Issue 5, pp. 1197-208, 2004 (PubMed).

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