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產品名稱：rLq2
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產品廠商：BioLeaf
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rLq2

詳情介紹：

Product details
Product details
Sequence	QFTQESCTAS NQCWSICKRL HNTNRGKCMN KKCRCYS.
Specificity	Lq2 inhibits Kir1.1 K inward rectifier channels , as well as KCa channels .
Characteristics	Source: Leiurus quinquestriatus hebraeus (Yellow scorpion). Molecular formula: C₁₇₇H₂₈₀N₆₀O₅₅S₇. Disulfide bonds between Cys7-Cys28, Cys13-Cys33 and Cys17-Cys35.
Purity	> 98 %

Target details
Target details
Molecular Weight	4353

Application Details
Application Details
Application Notes	5-50 nM
Comment	K+ channel toxin -KTx 1.2, Charybdotoxin-2, ChTX-Lq2, ChTx-d, Toxin 18-2, Lqh 18-2
Restrictions	For Research Use only

Handling
Handling
Format	Lyophilized
Reconstitution	Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min). Concentration after reconstitution: Dissolving 50g in 1.150 ml will provide a stock solution of 10 M.
Handling Advice	Soluble in Water.

References
References
Product cited in:	Lu, MacKinnon: "Purification, characterization, and synthesis of an inward-rectifier K+ channel inhibitor from scorpion venom." in: Biochemistry, Vol. 36, Issue 23, pp. 6936-40, 1997 (PubMed). Lucchesi, Ravindran, Young, Moczydlowski: "Analysis of the blocking activity of charybdotoxin homologs and iodinated derivatives against Ca2+-activated K+ channels." in: The Journal of membrane biology, Vol. 109, Issue 3, pp. 269-81, 1989 (PubMed).

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